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But of course, like any immutable system, there are mutable parts (otherwise, we couldn’t create any configuration files). OSTree handles this with “overlays” (actually, we use OverlayFS) that allow a read-write filesystem to be layered on top of the immutable system. For example, the /etc and /var directories are writable, while the rest of the system is read-only.
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在CNP类似物赛道，Ascendis的TransCon-CNP率先实现了剂型升级。与Vosoritide不一样的设计是TransCon-CNP被一层保护分子包裹，降低了体内清除影响，延长作用时间，实现每周一次给药。非头对头临床数据显示，TransCon-CNP每年2.29厘米的增高表现也优于Vosoritide。
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